Designation: Team Leader
Job Location: Bangalore
Department: Discovery Biology
About Syngene: Syngene (www.syngeneintl.com) is an innovation-led contract research, development and manufacturing organization offering integrated scientific services from early discovery to commercial supply.
At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures and SOPs, in letter and spirit
Mandatory expectation for all roles as per Syngene safety guidelines
- Overall adherence to safe practices and procedures of oneself and the teams aligned
- Contributing to development of procedures, practices and systems that ensures safe operations and compliance to company’s integrity & quality standards
- Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
- Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
- Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self
- Compliance to Syngene’ s quality standards at all times
- Hold self and their teams accountable for the achievement of safety goals
- Govern and Review safety metrics from time to time
Job Purpose
Looking for a highly innovative, enthusiastic and result-oriented individual who will lead a team of scientists, interfacing with the clients for their research and business needs and managing the activities of the Assay Development Group complying with the company quality and regulatory standards. The candidate will be involved in guiding the team for the development & qualification of different types of cell free biochemical and biophysical assays as part of the integrated and standalone projects.
Key Responsibilities:
- Scientifically contributing and leading the client FTE projects on cell free assays, regular updates and communications to internal and external customers on the progress of the project
- Manage a team of Scientists- Masters [includes goal setting, understanding developmental needs, assigning responsibilities in the laboratory activities, critically assessing their performance and providing timely feedback]
- Scientific execution of work, developing new assays, troubleshooting the assays, data analysis and presentations
- Active participation in the strategic drives- Data Integrity and Safety; Compound management & automation based on experience
- Writing and Review of Laboratory Note Books, Raw data and study report to ensure data integrity for himself/herself and for reporting team.
- Review reports and protocol of method development, qualification, and other studies
- Responsible for detailed planning of sample analysis and execution of protocol based studies.
- Technical data presentation in departmental and functional meetings.
- Maintains compliance with all company policies and procedures.
- Ability to build a small team and manage the daily activities of the assay group managing biochemical assays for drug discovery projects
Syngene Values:
All employees will consistently demonstrate alignment with our core values
- Excellence
- Integrity
- Professionalism
Accountabilities as a Syngene Leader:
- Champion effective Environment, Occupational Health, Safety and Sustainability (EHSS) practices for the company and oversee compliance with those practices within Biologics business. Play an active leadership role in monitoring and verifying safety performance through Gemba walks and other safety-led activities.
- Foster a corporate culture that promotes an environment, occupational health, safety, and sustainability (EHSS) mindset as well as the highest standards of quality, integrity, and compliance.
- Put people at the heart of our success by providing clear, active leadership defined by the Syngene leadership framework setting high standards of people management, career planning and talent retention as a priority.
Qualification: PhD in life science/biochemistry/biotechnology with 3-6 years
Technical Skills:
- Strong technical expertise in developing biochemical and biophysical assays, activity/ binding assays in multiple assay formats e.g. HTRF, FP, TR-FRET, AlphaLISA, Luminescence, DSF, MST, SPR, Thermal Shift or label-free technologies etc.
- Strong experience in conducting enzyme kinetic studies for MoA determination of small molecules e.g. Covalent inhibition, irreversible and reversible inhibition, Ki, Kinact/Ki determination etc.; binding affinity determinations and protein-protein interactions.
- Biochemical assay expertise for establishing assays for high throughput screening eg in 384 well format
- Experience and good track record for screening of compounds in primary assays driving SAR for discovery projects
- Knowledge of QC parameters for compound screening in biochemical assays for various target classes
- Interacts with other members of the department in developing innovative technologies and assay platform.
- Knowledge in regulatory guidelines related to biosafety, and statistical data analysis.
Behavioral Skills:
- Ability to manage a team of professionals to deliver quality work within the time frame, train and coach junior scientists, inculcate good work ethics.
- Ability to work with co‐workers and outside agencies professionally and tactfully.
- Excellent verbal/written communication and ability to communicate effectively with high transparency is essential.
- Interpersonal skills with an emphasis on working in a team environment to accomplish impactful results.
Equal Opportunity Employer:
It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.
